KIT Mutations Are Common in Testicular Seminomas

Expression of KIT tyrosine kinase is critical for normal germ cell development and is observed in the majority of seminomas. Activating mutations in KIT are common in gastrointestinal stromal tumors and mastocytosis. In this study we examined the frequency and spectrum of KIT mutations in 54 testicu...

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Detalhes bibliográficos
Main Authors: Kemmer, Kathleen, Corless, Christopher L., Fletcher, Jonathan A., McGreevey, Laura, Haley, Andrea, Griffith, Diana, Cummings, Oscar W., Wait, Cecily, Town, Ajia, Heinrich, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602213/
https://ncbi.nlm.nih.gov/pubmed/14695343
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