Mitotic recombination as evidence of alternative pathogenesis of gastrointestinal stromal tumours in neurofibromatosis type 1

BACKGROUND: Neurofibromatosis type 1 (NF1) is a neurocutaneous disorder resulting in the growth of a variety of tumours, and is inherited in an autosomal dominant pattern. Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours that commonly harbour oncogenic mutations in KIT or PDGFRA and...

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Detalhes bibliográficos
Principais autores: Stewart, Douglas R, Corless, Christopher L, Rubin, Brian P, Heinrich, Michael C, Messiaen, Ludwine M, Kessler, Lisa J, Zhang, Paul J, Brooks, David G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Electronic Letter
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597901/
https://ncbi.nlm.nih.gov/pubmed/17209131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2006.043075
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