Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach

Ménétrier disease and gastrointestinal stromal tumors (GISTs) are hyperproliferative disorders of the stomach caused by dysregulated receptor tyrosine kinases (RTKs). In Ménétrier disease, overexpression of TGF-α, a ligand for the RTK EGFR, results in selective expansion of surface mucous cells in t...

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Detalles Bibliográficos
Autores principales: Coffey, Robert J., Washington, Mary Kay, Corless, Christopher L., Heinrich, Michael C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2007
Materias:
Review Series
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716220/
https://ncbi.nlm.nih.gov/pubmed/17200708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30491
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