Affinity of monoclonal antibodies for Globo-series glycans

Por Eller, Chelcie H., Yang, Guangbin, Ouerfelli, Ouathek, Raines, Ronald T.
Publicado no Carbohydr Res (2014)

A Protecting Group-Free Synthesis of Deazathiamine: A Step Toward Inhibitor Design

Por Zhao, Hong, de Carvalho, Luiz Pedro S., Nathan, Carl, Ouerfelli, Ouathek
Publicado em 2010

Synthesis of Human Cancer Associated Globo-H (MBr1) Glycosylamino Acid: Some Mechanistic and Conformational Reinvestigations

Por Zhu, Jianglong, Wan, Qian, Yang, Guangbin, Ouerfelli, Ouathek, Danishefsky, Samuel J.
Publicado em 2009

Inhibitors of Hedgehog Acyltransferase Block Sonic Hedgehog Signaling

Por Petrova, Elissaveta, Rios-Esteves, Jessica, Ouerfelli, Ouathek, Glickman, J. Fraser, Resh, Marilyn D.
Publicado em 2013

Structure and Activity of Human Mitochondrial Peptide Deformylase, a Novel Cancer Target

Por Escobar-Alvarez, Sindy, Goldgur, Yehuda, Yang, Guangli, Ouerfelli, Ouathek, Li, Yueming, Scheinberg, David A.
Publicado em 2009

Radiosynthesis of the Tumor Hypoxia Marker [(18)F]TFMISO via O-[(18)F]Trifluoroethylation Reveals a Striking Difference Between Trifluoroethyl Tosylate and Iodide in Regiochemical...

Por Suehiro, Makiko, Yang, Guangbin, Torchon, Geralda, Ackerstaff, Ellen, Humm, John, Koutcher, Jason, Ouerfelli, Ouathek
Publicado em 2011

Stereo-controlled Synthesis of Novel Photoreactive γ-Secretase Inhibitors

Por Yang, Guangli, Yin, Ye Ingrid, Chun, Jiong, Shelton, Christopher C, Ouerfelli, Ouathek, Li, Yue-Ming
Publicado em 2008

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

Por Schneider, Christine, Sepp-Lorenzino, Laura, Nimmesgern, Elmar, Ouerfelli, Ouathek, Danishefsky, Samuel, Rosen, Neal, Hartl, F. Ulrich
Publicado em 1996

Mechanism of DNA Interstrand Crosslink Processing by Repair Nuclease FAN1

Por Wang, Renjing, Persky, Nicole, Yoo, Barney, Ouerfelli, Ouathek, Smogorzewska, Agata, Elledge, Stephen J., Pavletich, Nikola P.
Publicado no Science (2014)

Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims

Por Nagorny, Pavel, Krauss, Isaac, Njardarson, Jón T., Perez, Lucy, Gaul, Christoph, Yang, Guangli, Ouerfelli, Ouathek, Danishefsky, Samuel J.
Publicado em 2010

Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin

Por Lecomte, Nicolas, Njardarson, Jon T., Nagorny, Pavel, Yang, Guangli, Downey, Robert, Ouerfelli, Ouathek, Moore, Malcolm A. S., Danishefsky, Samuel J.
Publicado em 2011

Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function

Por Escobar-Alvarez, Sindy, Gardner, Jeffrey, Sheth, Aneesh, Manfredi, Giovanni, Yang, Guangli, Ouerfelli, Ouathek, Heaney, Mark L., Scheinberg, David A.
Publicado em 2010

N-Acetylgalactosamino Dendrons as Clearing Agents to Enhance Liver Targeting of Model Antibody-Fusion Protein

Por Yoo, Barney, Cheal, Sarah M., Torchon, Geralda, Dilhas, Anna, Yang, Guangbin, Pu, Jun, Punzalan, Blesida, Larson, Steven M., Ouerfelli, Ouathek
Publicado em 2013

Human Cancer Antigen Globo H Is a Cell-Surface Ligand for Human Ribonuclease 1

Por Eller, Chelcie H., Chao, Tzu-Yuan, Singarapu, Kiran K., Ouerfelli, Ouathek, Yang, Guangbin, Markley, John L., Danishefsky, Samuel J., Raines, Ronald T.
Publicado no ACS Cent Sci (2015)

Radiosynthesis of [(131)I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker — is specific activity a factor influencing hypoxia-mapping ability...

Por Suehiro, Makiko, Burgman, Paul, Carlin, Sean, Burke, Sean, Yang, Guangbin, Ouerfelli, Ouathek, Oehler-Janne, Christoph, O’Donoghue, Joseph, Ling, Clifton, Humm, John
Publicado em 2009

From Synthesis to Biologics: Preclinical Data on a Chemistry Derived Anticancer Vaccine

Por Zhu, Jianglong, Wan, Qian, Lee, Dongjoo, Yang, Guangbin, Spassova, Maria K., Ouerfelli, Ouathek, Ragupathi, Govind, Damani, Payal, Livingston, Philip O., Danishefsky, Samuel J.
Publicado em 2009

Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis: In vivo and Mechanistic Studies on the Migrastatin Core E...

Por Oskarsson, Thordur, Nagorny, Pavel, Krauss, Isaac, Perez, Lucy, Mandal, Mihiribaran, Yang, Guangli, Ouerfelli, Ouathek, Xiao, Danhua, Moore, Malcolm, Massagué, Joan, Danishefsky, Samuel J.
Publicado em 2010

Activity-based metabolomic profiling of enzymatic function: Identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase

Por de Carvalho, Luiz Pedro S., Zhao, Hong, Dickinson, Caitlyn E., Arango, Nancy M., Lima, Christopher D., Fischer, Steven M., Ouerfelli, Ouathek, Nathan, Carl, Rhee, Kyu Y.
Publicado em 2010

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

Por Somwar, Romel, Erdjument-Bromage, Hediye, Larsson, Erik, Shum, David, Lockwood, William W., Yang, Guangli, Sander, Chris, Ouerfelli, Ouathek, Tempst, Paul J., Djaballah, Hakim, Varmus, Harold E.
Publicado em 2011

High-Throughput Identification of Inhibitors of Human Mitochondrial Peptide Deformylase

Por ANTCZAK, CHRISTOPHE, SHUM, DAVID, ESCOBAR, SINDY, BASSIT, BHRAMDEO, KIM, EARL, SESHAN, VENKATRAMAN E., WU, NIAN, YANG, GUANGLI, OUERFELLI, OUATHEK, LI, YUE-MING, SCHEINBERG, DAVID A., DJABALLAH, HAKIM
Publicado em 2007