A blast from the past: ROS1 on the brain

Por Odintsov, Igor, Somwar, Romel, Davare, Monika A.
Publicado no Oncotarget (2019)

Identification and preliminary characterization of novel small molecules that inhibit growth of human lung adenocarcinoma cells

Por Somwar, Romel, Shum, David, Djaballah, Hakim, Varmus, Harold
Publicado em 2009

RASA1 and NF1 are preferentially co-mutated and define a distinct genetic subset of smoking-associated non-small cell lung carcinomas sensitive to MEK inhibition.

Por Hayashi, Takuo, Desmeules, Patrice, Smith, Roger S., Drilon, Alexander, Somwar, Romel, Ladanyi, Marc
Publicado no Clin Cancer Res (2017)

Single-cell analysis of insulin-regulated fatty acid uptake in adipocytes

Por Varlamov, Oleg, Somwar, Romel, Cornea, Anda, Kievit, Paul, Grove, Kevin L., Roberts, Charles T.
Publicado em 2010

Induction of BIM Is Essential for Apoptosis Triggered by EGFR Kinase Inhibitors in Mutant EGFR-Dependent Lung Adenocarcinomas

Por Gong, Yixuan, Somwar, Romel, Politi, Katerina, Balak, Marissa, Chmielecki, Juliann, Jiang, Xuejun, Pao, William
Publicado em 2007

Dosimetry of (18)F-Labeled Tyrosine Kinase Inhibitor SKI-249380, a Dasatinib-Tracer for PET Imaging

Por Dunphy, Mark P. S., Zanzonico, Pat, Veach, Darren, Somwar, Romel, Pillarsetty, Nagavarakishore, Lewis, Jason, Larson, Steven
Publicado em 2012

Protein Kinase B/Akt Participates in GLUT4 Translocation by Insulin in L6 Myoblasts

Por Wang, Qinghua, Somwar, Romel, Bilan, Philip J., Liu, Zhi, Jin, Jing, Woodgett, James R., Klip, Amira
Publicado em 1999

Spatiotemporal dynamics of triglyceride storage in unilocular adipocytes

Por Chu, Michael, Sampath, Harini, Cahana, David Y., Kahl, Christoph A., Somwar, Romel, Cornea, Anda, Roberts, Charles T., Varlamov, Oleg
Publicado no Mol Biol Cell (2014)

Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

Por Pao, William, Miller, Vincent A, Politi, Katerina A, Riely, Gregory J, Somwar, Romel, Zakowski, Maureen F, Kris, Mark G, Varmus, Harold
Publicado em 2005

Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma

Por Wang, Dunrui, Narula, Navneet, Azzopardi, Stephanie, Smith, Roger S., Nasar, Abu, Altorki, Nasser K., Mittal, Vivek, Somwar, Romel, Stiles, Brendon M., Du, Yi-Chieh Nancy
Publicado no Oncotarget (2016)

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

Por Somwar, Romel, Erdjument-Bromage, Hediye, Larsson, Erik, Shum, David, Lockwood, William W., Yang, Guangli, Sander, Chris, Ouerfelli, Ouathek, Tempst, Paul J., Djaballah, Hakim, Varmus, Harold E.
Publicado em 2011

Protein interaction mapping with ribosome-displayed using PLATO ORF libraries

Por Zhu, Jian, Larman, H. Benjamin, Gao, Geng, Somwar, Romel, Zhang, Zijuan, Laserson, Uri, Ciccia, Alberto, Pavlova, Natalya, Church, George, Zhang, Wei, Kesari, Santosh, Elledge, Stephen J.
Publicado em 2013

Protein interaction discovery using parallel analysis of translated ORFs (PLATO)

Por Zhu, Jian, Larman, H. Benjamin, Gao, Geng, Somwar, Romel, Zhang, Zijuan, Laserson, Uri, Ciccia, Alberto, Pavlova, Natalya, Church, George, Zhang, Wei, Kesari, Santosh, Elledge, Stephen J.
Publicado em 2013

LPTO-04. GENERATION AND CHARACTERIZATION OF PATIENT-DERIVED PRECLINICAL MODELS FROM TUMOR CELLS ISOLATED FROM CEREBROSPINAL FLUID

Por Offin, Michael, Vojnic, Morana, Liu, Zebing, Lui, Allan, Siau, Evan, Gladstone, Eric, Mattar, Marissa, Khodos, Inna, Drilon, Alexander, Boire, Adrienne, Rudin, Charles, De Stanchina, Elisa, Ladanyi, Marc, Somwar, Romel
Publicado no Neurooncol Adv (2019)

Acquired MET Exon 14 Alteration Drives Secondary Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in EGFR-Mutated Lung Cancer

Por Suzawa, Ken, Offin, Michael, Schoenfeld, Adam J., Plodkowski, Andrew J., Odintsov, Igor, Lu, Daniel, Lockwood, William W., Arcila, Maria E., Rudin, Charles M., Drilon, Alexander, Yu, Helena A., Riely, Gregory J., Somwar, Romel, Ladanyi, Marc
Publicado no JCO Precis Oncol (2019)

A Phase 2 Single Arm Trial of Cabozantinib in Patients with Advanced RET-Rearranged Lung Cancers

Por Drilon, Alexander, Rekhtman, Natasha, Arcila, Maria, Wang, Lu, Ni, Andy, Albano, Melanie, Van Voorthuysen, Martine, Somwar, Romel, Smith, Roger S., Montecalvo, Joseph, Plodkowski, Andrew, Ginsberg, Michelle S., Riely, Gregory J., Rudin, Charles M., Ladanyi, Marc, Kris, Mark G.
Publicado no Lancet Oncol (2016)

Concurrent alterations in EGFR-mutant lung cancers associated with resistance to EGFR kinase inhibitors and characterization of MTOR as a mediator of resistance.

Por Yu, Helena A., Suzawa, Ken, Jordan, Emmet, Zehir, Ahmet, Ni, Ai, Kim, Ryan, Kris, Mark G., Hellmann, Matthew D., Li, Bob T., Somwar, Romel, Solit, David B., Berger, Michael F., Arcila, Maria, Riely, Gregory J., Ladanyi, Marc
Publicado no Clin Cancer Res (2018)

Rare but recurrent ROS1 fusions resulting from chromosome 6q22 microdeletions are targetable oncogenes in glioma

Por Davare, Monika A., Henderson, Jacob J., Agarwal, Anupriya, Wagner, Jacob P., Iyer, Sudarshan R., Shah, Nameeta, Woltjer, Randy, Somwar, Romel, Gilheeney, Stephen W., DeCarvalo, Ana, Mikkelson, Tom, Van Meir, Erwin G., Ladanyi, Marc, Druker, Brian J.
Publicado no Clin Cancer Res (2018)

Antitumor Activity of RXDX-105 in Multiple Cancer Types with RET Rearrangements or Mutations

Por Li, Gang G., Somwar, Romel, Joseph, James, Smith, Roger S., Hayashi, Takuo, Martin, Leenus, Franovic, Aleksandra, Schairer, Anni, Martin, Eric, Riely, Gregory J., Harris, Jason, Yan, Shunqi, Wei, Ge, Oliver, Jennifer W., Patel, Rupal, Multani, Pratik, Ladanyi, Marc, Drilon, Alexander
Publicado no Clin Cancer Res (2016)

An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

Por Chitale, Dhananjay, Gong, Yixuan, Taylor, Barry S., Broderick, Stephen, Brennan, Cameron, Somwar, Romel, Golas, Benjamin, Wang, Lu, Motoi, Noriko, Szoke, Janos, Reinersman, J. Matthew, Major, John, Sander, Chris, Seshan, Venkatraman E., Zakowski, Maureen F., Rusch, Valerie, Pao, William, Gerald, William, Ladanyi, Marc
Publicado em 2009