LPTO-04. GENERATION AND CHARACTERIZATION OF PATIENT-DERIVED PRECLINICAL MODELS FROM TUMOR CELLS ISOLATED FROM CEREBROSPINAL FLUID

BACKGROUND: CNS metastases occur in 20–50% of lung cancer patients during their disease; leptomeningeal disease (LMD) representing 5–8%, classically carries a poor prognosis with a median overall survival ranging from 1–11 months. There is a paucity of patient-derived preclinical disease models usin...

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Publicat a:Neurooncol Adv
Autors principals: Offin, Michael, Vojnic, Morana, Liu, Zebing, Lui, Allan, Siau, Evan, Gladstone, Eric, Mattar, Marissa, Khodos, Inna, Drilon, Alexander, Boire, Adrienne, Rudin, Charles, De Stanchina, Elisa, Ladanyi, Marc, Somwar, Romel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Abstracts
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213369/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdz014.027
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