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Dosimetry of (18)F-Labeled Tyrosine Kinase Inhibitor SKI-249380, a Dasatinib-Tracer for PET Imaging
PURPOSE: To obtain estimates of human normal-organ radiation doses of (18)F-SKI-249380, as a prerequisite step towards first-in-human trial. (18)F-SKI-249380 is a first-of-its-kind PET tracer for imaging the in vivo pharmacokinetics of dasatinib, an investigational targeted therapy for solid maligna...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113455/ https://ncbi.nlm.nih.gov/pubmed/21161687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0462-2 |
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