Yüklüyor......

Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

BACKGROUND: Lung adenocarcinomas from patients who respond to the tyrosine kinase inhibitors gefitinib (Iressa) or erlotinib (Tarceva) usually harbor somatic gain-of-function mutations in exons encoding the kinase domain of the epidermal growth factor receptor (EGFR). Despite initial responses, pati...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Pao, William, Miller, Vincent A, Politi, Katerina A, Riely, Gregory J, Somwar, Romel, Zakowski, Maureen F, Kris, Mark G, Varmus, Harold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC549606/
https://ncbi.nlm.nih.gov/pubmed/15737014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0020073
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!