Morphologic Features of Adenocarcinoma of the Lung Predictive of Response to the Epidermal Growth Factor Receptor Kinase Inhibitors Erlotinib and Gefitinib

CONTEXT: A subset of lung adenocarcinomas appears preferentially sensitive to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). EGFR-activating mutations and never smoking are associated with response to TKIs. OBJECTIVES: To describe the morphology of adenocarcinomas respons...

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Detalhes bibliográficos
Main Authors: Zakowski, Maureen F., Hussain, Sanaa, Pao, William, Ladanyi, Marc, Ginsberg, Michelle S., Heelan, Robert, Miller, Vincent A., Rusch, Valerie W., Kris, Mark G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016915/
https://ncbi.nlm.nih.gov/pubmed/19260752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1043/1543-2165-133.3.470
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