A carregar...

Phase II Trial of Dasatinib for Patients with Acquired Resistance to Treatment with the Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors Erlotinib or Gefitinib

INTRODUCTION: Dual inhibition of SRC and EGFR -dependent pathways may overcome acquired resistance to EGFR-TKIs for patients with lung adenocarcinoma with EGFR mutations. The SRC-inhibitor dasatinib demonstrates anti-tumor activity in gefitinib-resistant cells lines and xenografts. Dasatinib is tole...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Johnson, Melissa L., Riely, Greg J., Rizvi, Naiyer A., Azzoli, Christopher G., Kris, Mark G., Sima, Camelia S., Ginsberg, Michelle S., Pao, William, Miller, Vincent A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230574/
https://ncbi.nlm.nih.gov/pubmed/21623279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3182161508
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!