Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

od Pao, William, Chmielecki, Juliann
Izdano 2010

Effects of Pharmacokinetic Processes and Varied Dosing Schedules on the Dynamics of Acquired Resistance to Erlotinib in EGFR-Mutant Lung Cancer

od Foo, Jasmine, Chmielecki, Juliann, Pao, William, Michor, Franziska
Izdano 2012

Induction of BIM Is Essential for Apoptosis Triggered by EGFR Kinase Inhibitors in Mutant EGFR-Dependent Lung Adenocarcinomas

od Gong, Yixuan, Somwar, Romel, Politi, Katerina, Balak, Marissa, Chmielecki, Juliann, Jiang, Xuejun, Pao, William
Izdano 2007

New Strategies in Overcoming Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer

od Oxnard, Geoffrey R., Arcila, Maria E., Chmielecki, Juliann, Ladanyi, Marc, Miller, Vincent A., Pao, William
Izdano 2011

Genomic analysis of 63,220 tumors reveals insights into tumor uniqueness and targeted cancer immunotherapy strategies

od Hartmaier, Ryan J., Charo, Jehad, Fabrizio, David, Goldberg, Michael E., Albacker, Lee A., Pao, William, Chmielecki, Juliann
Izdano u Genome Med (2017)

Signaling through ShcA Is Required for Transforming Growth Factor β- and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion

od Northey, Jason J., Chmielecki, Juliann, Ngan, Elaine, Russo, Caterina, Annis, Matthew G., Muller, William J., Siegel, Peter M.
Izdano 2008

GE-07 THE GENOMIC LANDSCAPE OF DIVERSE BRAIN TUMORS REVEALS KNOWN AND NOVEL ONCOGENIC ALTERATIONS FREQUENTLY ASSOCIATED WITH SENSITIVITY TO TARGETED INHIBITORS

od Chmielecki, Juliann, Frampton, Garrett, Morosini, Deborah, Ali, Siraj, Lipson, Doron, Yelensky, Roman, Ross, Jeffrey, Miller, Vincent, Stephens, Philip
Izdano 2014

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

od Albacker, Lee A., Wu, Jeremy, Smith, Peter, Warmuth, Markus, Stephens, Philip J., Zhu, Ping, Yu, Lihua, Chmielecki, Juliann
Izdano u PLoS One (2017)

A Novel PRKAR1B-BRAF Fusion in Gastrointestinal Stromal Tumor Guides Adjuvant Treatment Decision-Making During Pregnancy

od Charo, Lindsey M., Burgoyne, Adam M., Fanta, Paul T., Patel, Hitendra, Chmielecki, Juliann, Sicklick, Jason K., McHale, Michael T.
Izdano u J Natl Compr Canc Netw (2018)

Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer

od Chmielecki, Juliann, Peifer, Martin, Jia, Peilin, Socci, Nicholas D., Hutchinson, Katherine, Viale, Agnes, Zhao, Zhongming, Thomas, Roman K., Pao, William
Izdano 2010

Next-Generation Sequencing in the Clinical Setting Clarifies Patient Characteristics and Potential Actionability

od Bieg-Bourne, Cheyennedra C., Millis, Sherri Z., Piccioni, David E., Fanta, Paul T., Goldberg, Michael E., Chmielecki, Juliann, Parker, Barbara A., Kurzrock, Razelle
Izdano u Cancer Res (2017)

Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation

od Oxnard, Geoffrey R., Arcila, Maria E., Sima, Camelia S., Riely, Gregory J., Chmielecki, Juliann, Kris, Mark G., Pao, William, Ladanyi, Marc, Miller, Vincent A.
Izdano 2010

Meningioma transcription factors link cell lineage with systemic metabolic cues

od Du, Ziming, Brewster, Ryan, Merrill, Parker H, Chmielecki, Juliann, Francis, Josh, Aizer, Ayal, Abedalthagafi, Malak, Sholl, Lynette M, Geffers, Lars, Alexander, Brian, Santagata, Sandro
Izdano u Neuro Oncol (2018)

Exceptional durable response to everolimus in a patient with biphenotypic breast cancer harboring an STK11 variant

od Parachoniak, Christine A., Rankin, Andrew, Gaffney, Bernadette, Hartmaier, Ryan, Spritz, Dan, Erlich, Rachel L., Miller, Vincent A., Morosini, Deborah, Stephens, Phil, Ross, Jeffrey S., Keech, John, Chmielecki, Juliann
Izdano u Cold Spring Harb Mol Case Stud (2017)

EGFR mutant lung adenocarcinomas treated first-line with the novel EGFR inhibitor, XL647, can subsequently retain moderate sensitivity to erlotinib

od Chmielecki, Juliann, Pietanza, M. Catherine, Aftab, Dana, Shen, Ronglai, Zhao, Zhiguo, Chen, Xi, Hutchinson, Katherine, Viale, Agnes, Kris, Mark G., Stout, Thomas, Miller, Vincent, Rizvi, Naiyer, Pao, William
Izdano 2012

Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors

od Chmielecki, Juliann, Crago, Aimee M., Rosenberg, Mara, O'Connor, Rachael, Walker, Sarah R., Ambrogio, Lauren, Auclair, Daniel, McKenna, Aaron, Heinrich, Michael C., Frank, David A., Meyerson, Matthew
Izdano 2013

Oncogenic Alterations in ERBB2/HER2 Represent Potential Therapeutic Targets Across Tumors From Diverse Anatomic Sites of Origin

od Chmielecki, Juliann, Ross, Jeffrey S., Wang, Kai, Frampton, Garrett M., Palmer, Gary A., Ali, Siraj M., Palma, Norma, Morosini, Deborah, Miller, Vincent A., Yelensky, Roman, Lipson, Doron, Stephens, Philip J.
Izdano u Oncologist (2015)

Comprehensive Genomic Profiling Facilitates Implementation of the National Comprehensive Cancer Network Guidelines for Lung Cancer Biomarker Testing and Identifies Patients Who May...

od Suh, James H., Johnson, Adrienne, Albacker, Lee, Wang, Kai, Chmielecki, Juliann, Frampton, Garrett, Gay, Laurie, Elvin, Julia A., Vergilio, Jo-Anne, Ali, Siraj, Miller, Vincent A., Stephens, Philip J., Ross, Jeffrey S.
Izdano u Oncologist (2016)

Clinical impact of subclonal EGFR T790M mutations in advanced-stage EGFR-mutant non-small-cell lung cancers

od Vaclova, Tereza, Grazini, Ursula, Ward, Lewis, O’Neill, Daniel, Markovets, Aleksandra, Huang, Xiangning, Chmielecki, Juliann, Hartmaier, Ryan, Thress, Kenneth S., Smith, Paul D., Barrett, J. Carl, Downward, Julian, de Bruin, Elza C.
Izdano u Nat Commun (2021)

A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

od Brooks, Angela N., Choi, Peter S., de Waal, Luc, Sharifnia, Tanaz, Imielinski, Marcin, Saksena, Gordon, Pedamallu, Chandra Sekhar, Sivachenko, Andrey, Rosenberg, Mara, Chmielecki, Juliann, Lawrence, Michael S., DeLuca, David S., Getz, Gad, Meyerson, Matthew
Izdano 2014