Reversible inhibition of Hsp70 chaperone function by Scythe and Reaper

Por Thress, Kenneth, Song, Jaewhan, Morimoto, Richard I., Kornbluth, Sally
Publicado em 2001

Guide to detecting epidermal growth factor receptor (EGFR) mutations in ctDNA of patients with advanced non-small-cell lung cancer

Por Normanno, Nicola, Denis, Marc G., Thress, Kenneth S., Ratcliffe, Marianne, Reck, Martin
Publicado no Oncotarget (2016)

Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non–Small-Cell Lung Cancer

Por Oxnard, Geoffrey R., Thress, Kenneth S., Alden, Ryan S., Lawrance, Rachael, Paweletz, Cloud P., Cantarini, Mireille, Yang, James Chih-Hsin, Barrett, J. Carl, Jänne, Pasi A.
Publicado no J Clin Oncol (2016)

AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenografts

Por Iyer, Radhika, Varela, Carly R., Minturn, Jane E., Ho, Ruth, Simpson, Anisha M., Light, Jennifer E., Evans, Audrey E., Zhao, Huaqing, Thress, Kenneth, Brown, Jeffrey L., Brodeur, Garrett M.
Publicado no Cancer Chemother Pharmacol (2012)

Acquired EGFR C797S mediates resistance to AZD9291 in advanced non-small cell lung cancer harboring EGFR T790M

Por Thress, Kenneth S., Paweletz, Cloud P., Felip, Enriqueta, Cho, Byoung Chul, Stetson, Daniel, Dougherty, Brian, Lai, Zhongwu, Markovets, Aleksandra, Vivancos, Ana, Kuang, Yanan, Ercan, Dalia, Matthews, Sarah, Cantarini, Mireille, Barrett, J. Carl, Jänne, Pasi A., Oxnard, Geoffrey R.
Publicado no Nat Med (2015)

Discovery of Disubstituted Imidazo[4,5-b]pyridines and Purines as Potent TrkA Inhibitors

Por Wang, Tao, Lamb, Michelle L., Block, Michael H., Davies, Audrey Molina, Han, Yongxin, Hoffmann, Ethan, Ioannidis, Stephanos, Josey, John A., Liu, Zhong-Ying, Lyne, Paul D., MacIntyre, Terry, Mohr, Peter J., Omer, Charles A., Sjögren, Tove, Thress, Kenneth, Wang, Bin, Wang, Haiyun, Yu, Dingwei, Zhang, Hai-Jun
Publicado em 2012

Acquired resistance to mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling in preclinical models

Por Eberlein, Catherine A., Stetson, Daniel, Markovets, Aleksandra A., Al-Kadhimi, Katherine J., Lai, Zhongwu, Fisher, Paul R., Meador, Catherine B., Spitzler, Paula, Ichihara, Eiki, Ross, Sarah J., Ahdesmaki, Miika J., Ahmed, Ambar, Ratcliffe, Laura E., Christey O’Brien, Elizabeth L., Barnes, Claire H., Brown, Henry, Smith, Paul D., Dry, Jonathan R., Beran, Garry, Thress, Kenneth S., Dougherty, Brian, Pao, William, Cross, Darren A. E.
Publicado no Cancer Res (2015)