Chargement en cours...

AZ64 inhibits TrkB and enhances the efficacy of chemotherapy and local radiation in neuroblastoma xenografts

Neuroblastoma is a common pediatric tumor characterized by clinical heterogeneity. Because it is derived from sympathetic neuroblasts, the NTRK family of neurotrophin receptors plays an integral role in neuroblastoma cell survival, growth, and differentiation. Indeed, high expression of NTRK1 is ass...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cancer Chemother Pharmacol
Auteurs principaux: Iyer, Radhika, Varela, Carly R., Minturn, Jane E., Ho, Ruth, Simpson, Anisha M., Light, Jennifer E., Evans, Audrey E., Zhao, Huaqing, Thress, Kenneth, Brown, Jeffrey L., Brodeur, Garrett M.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4242714/
https://ncbi.nlm.nih.gov/pubmed/22623209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-012-1879-x
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!