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The Effect of P75 on Trk Receptors in Neuroblastomas

Neuroblastomas (NBs) with favorable outcome usually express TrkA, whereas unfavorable NBs frequently express TrkB and its cognate ligand BDNF. P75 (p75(LNTR), NGFR, TNFRSF16) binds NGF-related neurotrophins with low affinity and usually is co-expressed with Trk receptors in NBs. Here, we investigate...

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Hlavní autoři: Ho, Ruth, Minturn, Jane E., Simpson, Anisha M., Iyer, Radhika, Light, Jennifer E., Evans, Audrey E., Brodeur, Garrett M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070806/
https://ncbi.nlm.nih.gov/pubmed/21419569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.02.029
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