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The Effect of P75 on Trk Receptors in Neuroblastomas

Neuroblastomas (NBs) with favorable outcome usually express TrkA, whereas unfavorable NBs frequently express TrkB and its cognate ligand BDNF. P75 (p75(LNTR), NGFR, TNFRSF16) binds NGF-related neurotrophins with low affinity and usually is co-expressed with Trk receptors in NBs. Here, we investigate...

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Autores principales: Ho, Ruth, Minturn, Jane E., Simpson, Anisha M., Iyer, Radhika, Light, Jennifer E., Evans, Audrey E., Brodeur, Garrett M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070806/
https://ncbi.nlm.nih.gov/pubmed/21419569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.02.029
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