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The Effect of P75 on Trk Receptors in Neuroblastomas

Neuroblastomas (NBs) with favorable outcome usually express TrkA, whereas unfavorable NBs frequently express TrkB and its cognate ligand BDNF. P75 (p75(LNTR), NGFR, TNFRSF16) binds NGF-related neurotrophins with low affinity and usually is co-expressed with Trk receptors in NBs. Here, we investigate...

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Detalhes bibliográficos
Main Authors: Ho, Ruth, Minturn, Jane E., Simpson, Anisha M., Iyer, Radhika, Light, Jennifer E., Evans, Audrey E., Brodeur, Garrett M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070806/
https://ncbi.nlm.nih.gov/pubmed/21419569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.02.029
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