GE-07 THE GENOMIC LANDSCAPE OF DIVERSE BRAIN TUMORS REVEALS KNOWN AND NOVEL ONCOGENIC ALTERATIONS FREQUENTLY ASSOCIATED WITH SENSITIVITY TO TARGETED INHIBITORS

BACKGROUND: Brain tumors are complex cancers that range in behavior from aggressive to indolent. While some oncogenic alterations have been identified in these tumors, the efficacy of molecularly-matched targeted therapies has not been established. We sought to explore the spectrum of genomic altera...

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Main Authors: Chmielecki, Juliann, Frampton, Garrett, Morosini, Deborah, Ali, Siraj, Lipson, Doron, Yelensky, Roman, Ross, Jeffrey, Miller, Vincent, Stephens, Philip
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218211/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou256.7
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