Prospective Comprehensive Genomic Profiling of Advanced Gastric Carcinoma Cases Reveals Frequent Clinically Relevant Genomic Alterations and New Routes for Targeted Therapies

BACKGROUND. Gastric cancer (GC) is a major global cancer burden and the second most common cause of global cancer-related deaths. The addition of anti-ERBB2 (HER2) targeted therapy to chemotherapy improves survival for ERBB2-amplified advanced GC patients; however, the majority of GC patients do not...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncologist
Prif Awduron: Ali, Siraj M., Sanford, Eric M., Klempner, Samuel J., Rubinson, Douglas A., Wang, Kai, Palma, Norma A., Chmielecki, Juliann, Yelensky, Roman, Palmer, Gary A., Morosini, Deborah, Lipson, Doron, Catenacci, Daniel V., Braiteh, Fadi, Erlich, Rachel, Stephens, Philip J., Ross, Jeffrey S., Ou, Sai-Hong Ignatius, Miller, Vincent A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: AlphaMed Press 2015
Pynciau:
Gastrointestinal Cancer
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425384/
https://ncbi.nlm.nih.gov/pubmed/25882375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0378
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