N-Acetylgalactosamino Dendrons as Clearing Agents to Enhance Liver Targeting of Model Antibody-Fusion Protein

Dendrimer clearing agents represent a unique class of compounds for use in multistep targeting (MST) in radioimmunotherapy and imaging. These compounds were developed to facilitate the removal of excess tumor-targeting monoclonal antibody (mAb) prior to administration of the radionuclide to minimize...

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Main Authors: Yoo, Barney, Cheal, Sarah M., Torchon, Geralda, Dilhas, Anna, Yang, Guangbin, Pu, Jun, Punzalan, Blesida, Larson, Steven M., Ouerfelli, Ouathek
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900322/
https://ncbi.nlm.nih.gov/pubmed/24147780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400333m
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