A N-acetylgalactosamino Dendron-Clearing Agent for High-Therapeutic Index DOTA-Hapten Pretargeted Radioimmunotherapy

Clearing agents (CAs) can rapidly remove non-localized targeting biomolecules from circulation for hepatic catabolism, thereby enhancing the therapeutic index (TI), especially for blood (marrow), of the subsequently administered radioisotope in any multi-step pretargeting strategy. Herein we describ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Bioconjug Chem
Main Authors: Cheal, Sarah M., Patel, Mitesh, Yang, Guangbin, Veach, Darren, Xu, Hong, Guo, Hong-fen, Zanzonico, Pat B., Axworthy, Donald B., Cheung, Nai-Kong V., Ouerfelli, Ouathek, Larson, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7212493/
https://ncbi.nlm.nih.gov/pubmed/31891487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.9b00736
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares