Evaluation of glycodendron and synthetically-modified dextran clearing agents for multi-step targeting of radioisotopes for molecular imaging and radioimmunotherapy

A series of N-acetylgalactosamine-dendrons (NAG-dendrons) and dextrans bearing biotin moieties were compared for their ability to complex with and sequester circulating bispecific anti-tumor antibody (scFv(4)) streptavidin (SA) fusion protein (scFv(4)-SA) in vivo, to improve tumor to normal tissue c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Cheal, Sarah M., Yoo, Barney, Boughdad, Sarah, Punzalan, Blesida, Yang, Guangbin, Dilhas, Anna, Torchon, Geralda, Pu, Jun, Axworthy, Don B., Zanzonico, Pat, Ouerfelli, Ouathek, Larson, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4270281/
https://ncbi.nlm.nih.gov/pubmed/24219178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp4003128
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados