Engineered cells as a test platform for radiohaptens in pretargeted imaging and radioimmunotherapy applications

Pretargeted imaging and radioimmunotherapy approaches are designed to have superior targeting properties over directly targeted antibodies but impose more complex pharmacology, which hinders efforts to optimize the ligands prior to human applications. Human embryonic kidney 293T cells expressing the...

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Detalhes bibliográficos
Publicado no:Bioconjug Chem
Main Authors: Dacek, Megan M., Veach, Darren R., Cheal, Sarah M., Carter, Lukas M., McDevitt, Michael R., Punzalan, Blesida, Vargas, Daniela Burnes, Kubik, Thomas Z., Monette, Sebastien, Santich, Brian H., Yang, Guangbin, Ouerfelli, Ouathek, Kesner, Adam L., Cheung, Nai-Kong V., Scheinberg, David A., Larson, Steven M., Krebs, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8284561/
https://ncbi.nlm.nih.gov/pubmed/33819023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.0c00595
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