Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

Por Ragupathi, Govind, Gardner, Jeffrey R, Livingston, Philip O, Gin, David Y
Publicado em 2011

Accelerated Tumor Growth Mediated by Sub-lytic Levels of Antibody-Induced Complement Activation is Associated with Activation of the PI3K/AKT Survival Pathway

Por Wu, Xiaohong, Ragupathi, Govind, Panageas, Katherine, Hong, Feng, Livingston, Philip O.
Publicado em 2013

Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine

Por Deng, Kai, Adams, Michelle M., Damani, Payal, Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
Publicado em 2008

Biologics through Chemistry: Total Synthesis of a Proposed Dual-Acting Vaccine Targeting Ovarian Cancer by Orchestration of Oligosaccharide and Polypeptide Domains

Por Zhu, Jianglong, Wan, Qian, Ragupathi, Govind, George, Constantine M., Livingston, Philip O., Danishefsky, Samuel J.
Publicado em 2009

Synthesis of sialyl Lewis(a) (sLe(a), CA19-9) and construction of an immunogenic sLe(a) vaccine

Por Ragupathi, Govind, Damani, Payal, Srivastava, Geeta, Srivastava, Om, Sucheck, Steven J., Ichikawa, Yoshi, Livingston, Philip O.
Publicado em 2009

Human Monoclonal Antibodies to Sialyl-Lewis (a) (CA19.9) with Potent CDC, ADCC and Anti-Tumor Activity

Por Sawada, Ritsuko, Sun, Shu-Man, Wu, Xiaohong, Hong, Feng, Ragupathi, Govind, Livingston, Philip O., Scholz, Wolfgang W.
Publicado em 2011

Preclinical Evaluation of the Synthetic Adjuvant SQS-21 and its Constituent Isomeric Saponins

Por Ragupathi, Govind, Damani, Payal, Deng, Kai, Adams, Michelle M., Hang, Jianfeng, George, Constantine, Livingston, Philip O., Gin, David Y.
Publicado em 2010

Impact of minimal tumor burden on antibody response to vaccination

Por Kim, Soo-Kie, Wu, Xiaohong, Ragupathi, Govind, Gathuru, John, Koide, Fusataka, Cheung, Nai-Kong, Panageas, Katherine, Livingston, Philip O.
Publicado em 2011

Design and Synthesis of Potent Quillaja Saponin Vaccine Adjuvants

Por Adams, Michelle M., Damani, Payal, Perl, Nicholas R., Won, Annie, Hong, Feng, Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
Publicado em 2010

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol

Por Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Tan, Derek S., Gin, David Y.
Publicado no Bioorg Med Chem (2014)

A High-throughput O-Glycopeptide Discovery Platform for Seromic Profiling

Por Blixt, Ola, Cló, Emiliano, Nudelman, Aaron S., Sørensen, Kasper Kildegaard, Clausen, Thomas, Wandall, Hans H., Livingston, Philip O., Clausen, Henrik, Jensen, Knud J.
Publicado em 2010

Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes

Por Chea, Eric K., Fernández-Tejada, Alberto, Damani, Payal, Adams, Michelle M., Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
Publicado em 2012

From Synthesis to Biologics: Preclinical Data on a Chemistry Derived Anticancer Vaccine

Por Zhu, Jianglong, Wan, Qian, Lee, Dongjoo, Yang, Guangbin, Spassova, Maria K., Ouerfelli, Ouathek, Ragupathi, Govind, Damani, Payal, Livingston, Philip O., Danishefsky, Samuel J.
Publicado em 2009

The Known Immunologically Active Components of Astragalus Account for Only a Small Proportion of the Immunological Adjuvant Activity When Combined with Conjugate Vaccines

Por Hong, Feng, Xiao, Weilie, Ragupathi, Govind, Lau, Clara B. S., Leung, Ping Chung, Yeung, K. Simon, George, Constantine, Cassileth, Barrie, Kennelly, Edward, Livingston, Philip O.
Publicado em 2010

Immunization with N-propionyl polysialic acid–KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal aga...

Por Krug, Lee M., Ragupathi, Govind, Hood, Chandra, George, Constantine, Hong, Feng, Shen, Ronglai, Abrey, Lauren, Jennings, Harold J., Kris, Mark G., Livingston, Philip O.
Publicado em 2011

On the power of chemical synthesis: Immunological evaluation of models for multiantigenic carbohydrate-based cancer vaccines

Por Ragupathi, Govindaswami, Coltart, Don M., Williams, Lawrence J., Koide, Fusataka, Kagan, Ella, Allen, Jennifer, Harris, Christina, Glunz, Peter W., Livingston, Philip O., Danishefsky, Samuel J.
Publicado em 2002

Development of a minimal saponin vaccine adjuvant based on QS-21

Por Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.
Publicado em 2014

Applying PET to Broaden the Diagnostic Utility of the Clinically Validated CA19.9 Serum Biomarker for Oncology

Por Viola-Villegas, Nerissa Therese, Rice, Samuel L., Carlin, Sean, Wu, Xiaohong, Evans, Michael J., Sevak, Kuntal K., Drobjnak, Marija, Ragupathi, Govind, Sawada, Ritsuko, Scholz, Wolfgang W., Livingston, Philip O., Lewis, Jason S.
Publicado no J Nucl Med (2013)

Chemical and Genetic Assessment of Variability in Commercial Radix Astragali (Astragalus spp.) by Ion Trap LC-MS and Nuclear Ribosomal DNA Barcoding Sequence Analyses

Por XIAO, WEI-LIE, MOTLEY, TIMOTHY J., UNACHUKWU, UCHENNA J., LAU, CLARA BIK SAN, JIANG, BEI, HONG, FENG, LEUNG, PING-CHUNG, WANG, QING-FENG, LIVINGSTON, PHILIP O., CASSILETH, BARRIE R, KENNELLY, EDWARD J.
Publicado em 2011

Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: A phase I trial

Por Gilewski, Teresa, Ragupathi, Govindaswami, Bhuta, Sonal, Williams, Lawrence J., Musselli, Cristina, Zhang, Xu-Fang, Bencsath, Kalman P., Panageas, Katherine S., Chin, Jeanette, Hudis, Clifford A., Norton, Larry, Houghton, Alan N., Livingston, Philip O., Danishefsky, Samuel J.
Publicado em 2001