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Design and Synthesis of Potent Quillaja Saponin Vaccine Adjuvants

The success of antitumor and antiviral vaccines often requires the use of an adjuvant, a substance that significantly enhances the immune response to a co-administered antigen. Only a handful of adjuvants have both sufficient potency and acceptable toxicity for clinical investigation. One promising...

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Detalhes bibliográficos
Main Authors: Adams, Michelle M., Damani, Payal, Perl, Nicholas R., Won, Annie, Hong, Feng, Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820154/
https://ncbi.nlm.nih.gov/pubmed/20088518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9082842
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