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Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: A phase I trial

The carbohydrate antigen globo H commonly found on breast cancer cells is a potential target for vaccine therapy. The objectives of this trial were to determine the toxicity and immunogenicity of three synthetic globo H-keyhole limpet hemocyanin conjugates plus the immunologic adjuvant QS-21. Twenty...

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Detalhes bibliográficos
Main Authors: Gilewski, Teresa, Ragupathi, Govindaswami, Bhuta, Sonal, Williams, Lawrence J., Musselli, Cristina, Zhang, Xu-Fang, Bencsath, Kalman P., Panageas, Katherine S., Chin, Jeanette, Hudis, Clifford A., Norton, Larry, Houghton, Alan N., Livingston, Philip O., Danishefsky, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30643/
https://ncbi.nlm.nih.gov/pubmed/11248068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051626298
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