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Development of a minimal saponin vaccine adjuvant based on QS-21
Adjuvants are materials added to vaccines to enhance the immunological response to an antigen. QS-21 is a natural product adjuvant under investigation in numerous vaccine clinical trials, but its use is constrained by scarcity, toxicity, instability, and an enigmatic molecular mechanism of action. H...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215704/ https://ncbi.nlm.nih.gov/pubmed/24950335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1963 |
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