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Human Monoclonal Antibodies to Sialyl-Lewis (a) (CA19.9) with Potent CDC, ADCC and Anti-Tumor Activity
PURPOSE: The carbohydrate antigen sialyl-Lewis A (sLe(a)), also known as CA19.9, is widely expressed on epithelial tumors of the gastrointestinal tract and breast, and on small cell lung cancers. Since over-expression of sLe(a) appears to be a key event in invasion and metastasis of many tumors and...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074602/ https://ncbi.nlm.nih.gov/pubmed/21343375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2640 |
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