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High-Throughput Identification of Inhibitors of Human Mitochondrial Peptide Deformylase

The human mitochondrial peptide deformylase (HsPDF) provides a potential new target for broadly acting antiproliferative agents. To identify novel nonpeptidomimetic and nonhydroxamic acid–based inhibitors of HsPDF, the authors have developed a high-throughput screening (HTS) strategy using a fluores...

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Main Authors: ANTCZAK, CHRISTOPHE, SHUM, DAVID, ESCOBAR, SINDY, BASSIT, BHRAMDEO, KIM, EARL, SESHAN, VENKATRAMAN E., WU, NIAN, YANG, GUANGLI, OUERFELLI, OUATHEK, LI, YUE-MING, SCHEINBERG, DAVID A., DJABALLAH, HAKIM
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234356/
https://ncbi.nlm.nih.gov/pubmed/17435169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057107300463
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