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Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function
Deformylases are metalloproteases in bacteria, plants, and humans that remove the N-formyl-methionine off peptides in vitro. The human homolog of peptide deformylase (HsPDF) resides in the mitochondria, along with its putative formylated substrates; however, the cellular function of HsPDF remains el...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953058/ https://ncbi.nlm.nih.gov/pubmed/20805355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00469-10 |
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