Heat Shock Proteins in Disease – From Molecular Mechanisms to Therapeutics

Por Chiosis, Gabriela
Publicado no Curr Top Med Chem (2016)

Purine-Scaffold Hsp90 Inhibitors

Por Taldone, Tony, Chiosis, Gabriela
Publicado no Curr Top Med Chem (2009)

Assay for Isolation of Inhibitors of Her2-Kinase Expression

Por Chiosis, Gabriela, Keeton, Adam B.
Publicado em 2009

Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

Por Luo, Wenjie, Rodina, Anna, Chiosis, Gabriela
Publicado em 2008

Discovery and development of heat shock protein 90 inhibitors

Por Taldone, Tony, Sun, Weilin, Chiosis, Gabriela
Publicado em 2008

Chemical tools to investigate mechanisms associated with HSP90 and HSP70 in disease

Por Shrestha, Liza, Patel, Hardik J., Chiosis, Gabriela
Publicado no Cell Chem Biol (2016)

The epichaperome: the power of many as the power of one

Por Tai, Wang, Guzman, Monica L., Chiosis, Gabriela
Publicado no Oncoscience (2016)

Microwave-assisted one step synthesis of 8-arylmethyl-9H-purin-6-amines

Por Tao, Hui, Kang, Yanlong, Taldone, Tony, Chiosis, Gabriela
Publicado em 2008

Targeting Hsp90: small-molecule inhibitors and their clinical development

Por Taldone, Tony, Gozman, Alexander, Maharaj, Ronnie, Chiosis, Gabriela
Publicado em 2008

Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers

Por Jhaveri, Komal, Taldone, Tony, Modi, Shanu, Chiosis, Gabriela
Publicado em 2011

A global view of Hsp90 functions

Por Chiosis, Gabriela, Dickey, Chad A, Johnson, Jill L
Publicado em 2013

Advances in the discovery and development of heat-shock protein 90 inhibitors for cancer treatment

Por Patel, Hardik J, Modi, Shanu, Chiosis, Gabriela, Taldone, Tony
Publicado em 2011

Heat shock protein 90 in neurodegenerative diseases

Por Luo, Wenjie, Sun, Weilin, Taldone, Tony, Rodina, Anna, Chiosis, Gabriela
Publicado em 2010

The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1

Por Usmani, Saad Z, Bona, Robert D, Chiosis, Gabriela, Li, Zihai
Publicado em 2010

Heat Shock Protein gp96 regulates Toll-Like Receptor 9 proteolytic processing and conformational stability

Por Brooks, James C., Sun, Weilin, Chiosis, Gabriela, Leifer, Cynthia A.
Publicado em 2012

α7 Helix Region of αI Domain Is Crucial for Integrin Binding to Endoplasmic Reticulum Chaperone gp96: A POTENTIAL THERAPEUTIC TARGET FOR CANCER METASTASIS

Por Hong, Feng, Liu, Bei, Chiosis, Gabriela, Gewirth, Daniel T., Li, Zihai
Publicado em 2013

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Por Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Publicado em 2013

Selective targeting of the stress chaperome as a therapeutic strategy

Por Taldone, Tony, Ochiana, Stefan O., Patel, Pallav D., Chiosis, Gabriela
Publicado no Trends Pharmacol Sci (2014)

Synthesis of Reblastatin, Autolytimycin, Non-Benzoquinone Analogs: Potent Inhibitors of Heat Shock Protein 90 (Hsp90)

Por Wrona, Iwona E., Gozman, Alexander, Taldone, Tony, Chiosis, Gabriela, Panek, James S.
Publicado em 2010

Protein chaperones: a composition of matter review (2008 – 2013)

Por Taldone, Tony, Patel, Hardik J, Bolaender, Alexander, Patel, Maulik R, Chiosis, Gabriela
Publicado em 2014