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Chemical tools to investigate mechanisms associated with HSP90 and HSP70 in disease

The chaperome is a large and diverse protein machinery composed of chaperone proteins and a variety of helpers, such as the co-chaperones, folding enzymes and scaffolding and adapter proteins. Heat shock protein 90s and 70s (HSP90s and HSP70s), the most abundant chaperome members in human cells, are...

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Detalhes bibliográficos
Publicado no:Cell Chem Biol
Main Authors: Shrestha, Liza, Patel, Hardik J., Chiosis, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779498/
https://ncbi.nlm.nih.gov/pubmed/26933742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.12.006
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