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Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

Heat shock proteins (HSPs) present as a double edged sword. While they play an important role in maintaining protein homeostasis in a normal cell, cancer cells have evolved to co-opt HSP function to promote their own survival. As a result, HSPs such as HSP90 have attracted a great deal of interest a...

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Dettagli Bibliografici
Pubblicato in:Curr Top Med Chem
Autori principali: Shrestha, Liza, Bolaender, Alexander, Patel, Hardik J., Taldone, Tony
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995156/
https://ncbi.nlm.nih.gov/pubmed/27072696
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