Chemical tools to investigate mechanisms associated with HSP90 and HSP70 in disease

por Shrestha, Liza, Patel, Hardik J., Chiosis, Gabriela
Publicado en Cell Chem Biol (2016)

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

por Shrestha, Liza, Bolaender, Alexander, Patel, Hardik J., Taldone, Tony
Publicado en Curr Top Med Chem (2016)

Copper Mediated Coupling of 2-(Piperazine)-pyrimidine Iodides with Aryl Thiols using Cu(I)Thiophene-2-carboxylate

por Shrestha, Liza, Patel, Hardik J., Kang, Yanlong, Sharma, Sahil, Chiosis, Gabriela, Taldone, Tony
Publicado en Tetrahedron Lett (2017)

From medical images to flow computations without user-generated meshes

por Dillard, Seth I., Mousel, John A., Shrestha, Liza, Raghavan, Madhavan L., Vigmostad, Sarah C.
Publicado 2014

NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90

por Huck, John D., Que, Nanette L. S., Immormino, Robert M., Shrestha, Liza, Taldone, Tony, Chiosis, Gabriela, Gewirth, Daniel T.
Publicado en J Biol Chem (2019)

Evaluation of Substrate and Inhibitor Binding to Yeast and Human Isoprenylcysteine Carboxyl Methyltransferases (Icmts) using Biotinylated Benzophenone-containing Photoaffinity Prob...

por Hahne, Kalub, Vervacke, Jeffery, Shrestha, Liza, Donelson, James L., Gibbs, Richard A., Distefano, Mark D., Hrycyna, Christine A.
Publicado 2012

Amide-Modified Prenylcysteine based Icmt Inhibitors: Structure Activity Relationships, Kinetic Analysis and Cellular Characterization

por Majmudar, Jaimeen D., Hodges-Loaiza, Heather B., Hahne, Kalub, Donelson, James L., Song, Jiao, Shrestha, Liza, Harrison, Marietta L., Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2011

Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94

por Patel, Hardik J., Patel, Pallav D., Ochiana, Stefan O., Yan, Pengrong, Sun, Weilin, Patel, Maulik R., Shah, Smit K., Tramentozzi, Elisa, Brooks, James, Bolaender, Alexander, Shrestha, Liza, Stephani, Ralph, Finotti, Paola, Leifer, Cynthia, Li, Zihai, Gewirth, Daniel T., Taldone, Tony, Chiosis, Gabriela
Publicado en J Med Chem (2015)

Oncogenic hijacking of the stress response machinery in T cell acute lymphoblastic leukemia

por Kourtis, Nikos, Lazaris, Charalampos, Hockemeyer, Kathryn, Balandrán, Juan Carlos, Jimenez, Alejandra R., Mullenders, Jasper, Gong, Yixiao, Trimarchi, Thomas, Bhatt, Kamala, Hu, Hai, Shrestha, Liza, Ambesi-Impiombato, Alberto, Kelliher, Michelle, Paietta, Elisabeth, Chiosis, Gabriela, Guzman, Monica L., Ferrando, Adolfo A., Tsirigos, Aristotelis, Aifantis, Iannis
Publicado en Nat Med (2018)

Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer

por Rodina, Anna, Taldone, Tony, Kang, Yanlong, Patel, Pallav D., Koren, John, Yan, Pengrong, DaGama Gomes, Erica M., Yang, Chenghua, Patel, Maulik R., Shrestha, Liza, Ochiana, Stefan O., Santarossa, Cristina, Maharaj, Ronnie, Gozman, Alexander, Cox, Marc B., Erdjument-Bromage, Hediye, Hendrickson, Ronald C., Cerchietti, Leandro, Melnick, Ari, Guzman, Monica L., Chiosis, Gabriela
Publicado 2014