Functional Oligomerization of the Saccharomyces cerevisiae Isoprenylcysteine Carboxyl Methyltransferase, Ste14p

por Griggs, Amy M., Hahne, Kalub, Hrycyna, Christine A.
Publicado 2010

Inhibition of P-Glycoprotein-Mediated Paclitaxel Resistance by Reversibly Linked Quinine Homodimers

por Pires, Marcos M., Emmert, Dana, Hrycyna, Christine A., Chmielewski, Jean
Publicado 2009

Homodimers of the Antiviral Abacavir as Modulators of P-glycoprotein Transport in Cell Culture: Probing Tether Length

por Namanja, Hilda A., Emmert, Dana, Hrycyna, Christine A., Chmielewski, Jean
Publicado 2013

Non-Substrate Based, Small Molecule Inhibitors of the Human Isoprenylcysteine Carboxyl Methyltransferase

por Butler, Kyle V, Bohn, Kelsey, Hrycyna, Christine A., Jin, Jian
Publicado en Medchemcomm (2016)

THE ISOPRENOID SUBSTRATE SPECIFICITY OF ISOPRENYLCYSTEINE CARBOXYLMETHYLTRANSFERASE: DEVELOPMENT OF NOVEL INHIBITORS()

por Anderson, Jessica L., Henriksen, Brian S., Gibbs, Richard A., Hrycyna, Christine A.
Publicado 2005

Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: Sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors

por Majmudar, Jaimeen D., Hahne, Kalub, Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2011

Synthesis of desthio prenylcysteine analogs: sulfur is important for biological activity

por Henriksen, Brian S., Anderson, Jessica L., Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2005

Lipid and sulfur substituted prenylcysteine analogs as human Icmt inhibitors

por Bergman, Joel A., Hahne, Kalub, Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2011

The nature of amino acid 482 of human ABCG2 affects substrate transport and ATP hydrolysis but not substrate binding

por Ejendal, Karin F.K., Diop, Ndeye Khady, Schweiger, Linda C., Hrycyna, Christine A.
Publicado 2006

Functional Reconstitution of the Integral Membrane Enzyme, Isoprenylcysteine Carboxyl Methyltransferase, in Synthetic Bolalipid Membrane Vesicles

por Febo-Ayala, Wilma, Morera-Félix, Shakira L., Hrycyna, Christine A., Thompson, David H.
Publicado 2006

Inhibition of Human P-glycoprotein Transport and Substrate Binding Using a Galantamine Dimer

por Namanja, Hilda A., Emmert, Dana, Pires, Marcos M., Hrycyna, Christine A., Chmielewski, Jean
Publicado 2009

S-Farnesyl-Thiopropionic Acid Triazoles as Potent Inhibitors of Isoprenylcysteine Carboxyl Methyltransferase

por Bergman, Joel A., Hahne, Kalub, Song, Jiao, Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2011

Potential Tools for Eradicating HIV Reservoirs in the Brain: Development of Trojan Horse Prodrugs for the Inhibition of P-Glycoprotein with Anti-HIV-1 Activity

por Agrawal, Neha, Rowe, Jennifer, Lan, Jie, Yu, Qigui, Hrycyna, Christine A., Chmielewski, Jean
Publicado en J Med Chem (2019)

Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severity

por Barrowman, Jemima, Wiley, Patricia A., Hudon-Miller, Sarah E., Hrycyna, Christine A., Michaelis, Susan
Publicado 2012

Competency-Based Reforms of the Undergraduate Biology Curriculum: Integrating the Physical and Biological Sciences

por Thompson, Katerina V., Chmielewski, Jean, Gaines, Michael S., Hrycyna, Christine A., LaCourse, William R.
Publicado 2013

Solid-phase synthesis of prenylcysteine analogs

por Donelson, James L., Hodges-Loaiza, Heather B., Henriksen, Brian S., Hrycyna, Christine A., Gibbs, Richard A.
Publicado 2009

HIV-Protease Inhibitors Block the Enzymatic Activity of Purified Ste24p

por Hudon, Sarah E., Coffinier, Catherine, Michaelis, Susan, Fong, Loren G., Young, Stephen G., Hrycyna, Christine A.
Publicado 2008

Diazirine-Containing Photoactivatable Isoprenoid: Synthesis and Application in Studies with Isoprenylcysteine Carboxyl Methyltransferase

por Vervacke, Jeffrey S., Funk, Amy L., Wang, Yen-Chih, Strom, Mark, Hrycyna, Christine A., Distefano, Mark D.
Publicado 2014

ZMPSTE24 missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or protein stability

por Spear, Eric D., Hsu, Erh-Ting, Nie, Laiyin, Carpenter, Elisabeth P., Hrycyna, Christine A., Michaelis, Susan
Publicado en Dis Model Mech (2018)

Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-glycoprotein at the Blood-Brain Barrier with Prodrug Abacavir Dimers

por Namanja, Hilda A., Emmert, Dana, Davis, David A., Campos, Christopher, Miller, David S., Hrycyna, Christine A., Chmielewski, Jean
Publicado 2011