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HIV-Protease Inhibitors Block the Enzymatic Activity of Purified Ste24p
We reported that several HIV protease inhibitors (HIV-PIs) interfere with the endoproteolytic processing of two farnesylated proteins, yeast a-factor and mammalian prelamin A. We proposed that these drugs interfere with prelamin A processing by blocking ZMPSTE24, an integral membrane zinc metallopro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2543933/ https://ncbi.nlm.nih.gov/pubmed/18639527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.07.033 |
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