Diazirine-Containing Photoactivatable Isoprenoid: Synthesis and Application in Studies with Isoprenylcysteine Carboxyl Methyltransferase

[Image: see text] Photoaffinity labeling is a useful technique employed to identify protein–ligand and protein–protein noncovalent interactions. Photolabeling experiments have been particularly informative for probing membrane-bound proteins where structural information is difficult to obtain. The m...

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Detalhes bibliográficos
Main Authors: Vervacke, Jeffrey S., Funk, Amy L., Wang, Yen-Chih, Strom, Mark, Hrycyna, Christine A., Distefano, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985442/
https://ncbi.nlm.nih.gov/pubmed/24502619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo402600b
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