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Purine-Scaffold Hsp90 Inhibitors

Hsp90 is a molecular chaperone with important roles in regulating the function of several proteins with potential pathogenic activity. Because many of these proteins are involved in cancer and neurodegenerative promoting pathways, Hsp90 has emerged as an attractive therapeutic target in these diseas...

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Detalhes bibliográficos
Publicado no:Curr Top Med Chem
Main Authors: Taldone, Tony, Chiosis, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699796/
https://ncbi.nlm.nih.gov/pubmed/19860732
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