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Purine-Scaffold Hsp90 Inhibitors

Hsp90 is a molecular chaperone with important roles in regulating the function of several proteins with potential pathogenic activity. Because many of these proteins are involved in cancer and neurodegenerative promoting pathways, Hsp90 has emerged as an attractive therapeutic target in these diseas...

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Podrobná bibliografie
Vydáno v:Curr Top Med Chem
Hlavní autoři: Taldone, Tony, Chiosis, Gabriela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699796/
https://ncbi.nlm.nih.gov/pubmed/19860732
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