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Purine-Scaffold Hsp90 Inhibitors

Hsp90 is a molecular chaperone with important roles in regulating the function of several proteins with potential pathogenic activity. Because many of these proteins are involved in cancer and neurodegenerative promoting pathways, Hsp90 has emerged as an attractive therapeutic target in these diseas...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Top Med Chem
Main Authors: Taldone, Tony, Chiosis, Gabriela
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699796/
https://ncbi.nlm.nih.gov/pubmed/19860732
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