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Targeting Hsp90: small-molecule inhibitors and their clinical development
The Hsp90 multichaperone complex has important roles in the development and progression of malignant transformation. Several small-molecule inhibitors of Hsp90 of diverse chemotypes have shown potent antitumor activity in a wide-range of malignancies, and are currently in clinical or late-stage prec...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760289/ https://ncbi.nlm.nih.gov/pubmed/18644253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2008.06.015 |
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