A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)

BACKGROUND: Drug resistance, absence of an effective vaccine, and inadequate public health measures are major impediments to controlling Plasmodium falciparum malaria worldwide. The development of antimalarials to which resistance is less likely is paramount. To this end, we have exploited the chape...

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Detaylı Bibliyografya
Asıl Yazarlar: Shahinas, Dea, Folefoc, Asongna, Taldone, Tony, Chiosis, Gabriela, Crandall, Ian, Pillai, Dylan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787104/
https://ncbi.nlm.nih.gov/pubmed/24098696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075446
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