A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)

BACKGROUND: Drug resistance, absence of an effective vaccine, and inadequate public health measures are major impediments to controlling Plasmodium falciparum malaria worldwide. The development of antimalarials to which resistance is less likely is paramount. To this end, we have exploited the chape...

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Bibliographic Details
Main Authors: Shahinas, Dea, Folefoc, Asongna, Taldone, Tony, Chiosis, Gabriela, Crandall, Ian, Pillai, Dylan R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787104/
https://ncbi.nlm.nih.gov/pubmed/24098696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075446
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