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The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaques) and of tau protein, which form neurofibrilla...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Lackie, Rachel E., Maciejewski, Andrzej, Ostapchenko, Valeriy G., Marques-Lopes, Jose, Choy, Wing-Yiu, Duennwald, Martin L., Prado, Vania F., Prado, Marco A. M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433227/
https://ncbi.nlm.nih.gov/pubmed/28559789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00254
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