The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaques) and of tau protein, which form neurofibrilla...

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Detalles Bibliográficos
Publicado en:Front Neurosci
Main Authors: Lackie, Rachel E., Maciejewski, Andrzej, Ostapchenko, Valeriy G., Marques-Lopes, Jose, Choy, Wing-Yiu, Duennwald, Martin L., Prado, Vania F., Prado, Marco A. M.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433227/
https://ncbi.nlm.nih.gov/pubmed/28559789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00254
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