The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases

The accumulation of misfolded proteins in the human brain is one of the critical features of many neurodegenerative diseases, including Alzheimer's disease (AD). Assembles of beta-amyloid (Aβ) peptide—either soluble (oligomers) or insoluble (plaques) and of tau protein, which form neurofibrilla...

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Vydáno v:Front Neurosci
Hlavní autoři: Lackie, Rachel E., Maciejewski, Andrzej, Ostapchenko, Valeriy G., Marques-Lopes, Jose, Choy, Wing-Yiu, Duennwald, Martin L., Prado, Vania F., Prado, Marco A. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433227/
https://ncbi.nlm.nih.gov/pubmed/28559789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00254
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