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Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome
The de novo biosynthesis of purines is carried out by a highly conserved metabolic pathway that includes several validated targets for anticancer, immunosuppressant, and anti-inflammatory chemotherapeutics. The six enzymes in humans that catalyze the 10 chemical steps from phosphoribosylpyrophosphat...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574928/ https://ncbi.nlm.nih.gov/pubmed/23359685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300173110 |
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