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Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Al...

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Detalhes bibliográficos
Main Authors: Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172285/
https://ncbi.nlm.nih.gov/pubmed/25258700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0460.S10-007
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