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Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Al...

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Bibliografiske detaljer
Main Authors: Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172285/
https://ncbi.nlm.nih.gov/pubmed/25258700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0460.S10-007
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