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Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Al...

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Hlavní autoři: Carman, Aaron, Kishinevsky, Sarah, Koren, John, Lou, Wenjie, Chiosis, Gabriela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4172285/
https://ncbi.nlm.nih.gov/pubmed/25258700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2161-0460.S10-007
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