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Protein Quality Control by Molecular Chaperones in Neurodegeneration
Protein homeostasis (proteostasis) requires the timely degradation of misfolded proteins and their aggregates by protein quality control (PQC), of which molecular chaperones are an essential component. Compared with other cell types, PQC in neurons is particularly challenging because they have a uni...
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| Publié dans: | Front Neurosci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382173/ https://ncbi.nlm.nih.gov/pubmed/28428740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00185 |
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