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Protein Quality Control by Molecular Chaperones in Neurodegeneration

Protein homeostasis (proteostasis) requires the timely degradation of misfolded proteins and their aggregates by protein quality control (PQC), of which molecular chaperones are an essential component. Compared with other cell types, PQC in neurons is particularly challenging because they have a uni...

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Bibliografische gegevens
Gepubliceerd in:Front Neurosci
Hoofdauteurs: Ciechanover, Aaron, Kwon, Yong Tae
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382173/
https://ncbi.nlm.nih.gov/pubmed/28428740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00185
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