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Molecular chaperones, alpha-synuclein and neurodegeneration
Parkinson’s disease (PD) is a devastating neurological condition that affects about 1% of people older than 65 years of age. In PD, dopaminergic neurons in the midbrain slowly accumulate cytoplasmic inclusions (Lewy bodies, LBs) of the protein alpha-synuclein (α-syn) and then gradually lose function...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537861/ https://ncbi.nlm.nih.gov/pubmed/22923346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8325-2 |
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