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Molecular chaperones, alpha-synuclein and neurodegeneration

Parkinson’s disease (PD) is a devastating neurological condition that affects about 1% of people older than 65 years of age. In PD, dopaminergic neurons in the midbrain slowly accumulate cytoplasmic inclusions (Lewy bodies, LBs) of the protein alpha-synuclein (α-syn) and then gradually lose function...

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書目詳細資料
主要作者: Witt, Stephan N.
格式: Artigo
語言:Inglês
出版: 2012
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537861/
https://ncbi.nlm.nih.gov/pubmed/22923346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8325-2
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