Aplastic anemia: immunosuppressive therapy in 2010

Por Risitano, Antonio M., Perna, Fabiana
Publicado em 2011

L3MBTL1 Deficiency Directs the Differentiation of Human Embryonic Stem Cells Toward Trophectoderm

Por Hoya-Arias, Ruben, Tomishima, Mark, Perna, Fabiana, Voza, Francesca, Nimer, Stephen D.
Publicado em 2011

L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability

Por Gurvich, Nadia, Perna, Fabiana, Farina, Andrea, Voza, Francesca, Menendez, Silvia, Hurwitz, Jerard, Nimer, Stephen D.
Publicado em 2010

ETV6-ABL1-positive “chronic myeloid leukemia”: clinical and molecular response to tyrosine kinase inhibition

Por Perna, Fabiana, Abdel-Wahab, Omar, Levine, Ross L., Jhanwar, Suresh C., Imada, Kazunori, Nimer, Stephen D.
Publicado em 2011

Structural design of engineered costimulation determines tumor rejection kinetics and persistence of CAR T cells

Por Zhao, Zeguo, Condomines, Maud, van der Stegen, Sjoukje J.C., Perna, Fabiana, Kloss, Christopher C., Gunset, Gertrude, Plotkin, Jason, Sadelain, Michel
Publicado no Cancer Cell (2015)

Management of the HBV reactivation in isolated HBcAb positive patients affected with Non Hodgkin Lymphoma

Por Masarone, Mario, De Renzo, Amalia, La Mura, Vincenzo, Sasso, Ferdinando Carlo, Romano, Marco, Signoriello, Giuseppe, Rosato, Valerio, Perna, Fabiana, Pane, Fabrizio, Persico, Marcello
Publicado em 2014

Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis

Por Liu, Fan, Cheng, Guoyan, Hamard, Pierre-Jacques, Greenblatt, Sarah, Wang, Lan, Man, Na, Perna, Fabiana, Xu, Haiming, Tadi, Madhavi, Luciani, Luisa, Nimer, Stephen D.
Publicado no J Clin Invest (2015)

Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q− polycythemia vera

Por Perna, Fabiana, Gurvich, Nadia, Hoya-Arias, Ruben, Abdel-Wahab, Omar, Levine, Ross L., Asai, Takashi, Voza, Francesca, Menendez, Silvia, Wang, Lan, Liu, Fan, Zhao, Xinyang, Nimer, Stephen D.
Publicado em 2010

The Polycomb Group Protein L3MBTL1 Represses a SMAD5-Mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells

Por Perna, Fabiana, Vu, Ly P., Themeli, Maria, Kriks, Sonja, Hoya-Arias, Ruben, Khanin, Raya, Hricik, Todd, Mansilla-Soto, Jorge, Papapetrou, Eirini P., Levine, Ross L., Studer, Lorenz, Sadelain, Michel, Nimer, Stephen D.
Publicado no Stem Cell Reports (2015)

JAK2V617F-mediated phosphorylation of PRMT5 down-regulates its methyltransferase activity and promotes myeloproliferation

Por Liu, Fan, Zhao, Xinyang, Perna, Fabiana, Wang, Lan, Koppikar, Priya, Abdel-Wahab, Omar, Harr, Michael W., Levine, Ross L., Xu, Hao, Tefferi, Ayalew, Deblasio, Anthony, Hatlen, Megan, Menendez, Silvia, Nimer, Stephen D.
Publicado no Cancer Cell (2011)

PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex

Por Vu, Ly P., Perna, Fabiana, Wang, Lan, Voza, Francesca, Figueroa, Maria E., Tempst, Paul, Erdjument-Bromage, Hediye, Gao, Rui, Chen, Sisi, Paietta, Elisabeth, Deblasio, Tony, Melnick, Ari, Liu, Yan, Zhao, Xinyang, Nimer, Stephen D.
Publicado em 2013

MEF promotes stemness in the pathogenesis of gliomas

Por Bazzoli, Elena, Pulvirenti, Teodoro, Oberstadt, Moritz C., Perna, Fabiana, Wee, Boyoung, Schultz, Nikolaus, Huse, Jason T., Fomchenko, Elena I., Voza, Francesca, Tabar, Viviane, Brennan, Cameron W., DeAngelis, Lisa M., Nimer, Stephen D., Holland, Eric C., Squatrito, Massimo
Publicado em 2012

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

Por Kotini, Andriana G, Chang, Chan-Jung, Boussaad, Ibrahim, Delrow, Jeffrey J, Dolezal, Emily K, Nagulapally, Abhinav B, Perna, Fabiana, Fishbein, Gregory A, Klimek, Virginia M, Hawkins, R David, Huangfu, Danwei, Murry, Charles E, Graubert, Timothy, Nimer, Stephen D, Papapetrou, Eirini P
Publicado no Nat Biotechnol (2015)

The Leukemogenicity of AML1-ETO Is Dependent on Site-Specific Lysine Acetylation

Por Wang, Lan, Gural, Alexander, Sun, Xiao-Jian, Zhao, Xinyang, Perna, Fabiana, Huang, Gang, Hatlen, Megan A., Vu, Ly, Liu, Fan, Xu, Haiming, Asai, Takashi, Xu, Hao, Deblasio, Tony, Menendez, Silvia, Voza, Francesca, Jiang, Yanwen, Cole, Philip A., Zhang, Jinsong, Melnick, Ari, Roeder, Robert G., Nimer, Stephen D.
Publicado em 2011

ASXL1 Mutations Promote Myeloid Transformation Through Loss of PRC2-Mediated Gene Repression

Por Abdel-Wahab, Omar, Adli, Mazhar, LaFave, Lindsay M., Gao, Jie, Hricik, Todd, Shih, Alan H., Pandey, Suveg, Patel, Jay, Chung, Young Rock, Koche, Richard, Perna, Fabiana, Zhao, Xinyang, Taylor, Jordan E., Park, Christopher Y., Carroll, Martin, Melnick, Ari, Nimer, Stephen D., Jaffe, Jacob D., Aifantis, Iannis, Bernstein, Bradley E., Levine, Ross L
Publicado em 2012

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

Por Moran-Crusio, Kelly, Reavie, Linsey, Shih, Alan, Abdel-Wahab, Omar, Ndiaye-Lobry, Delphine, Lobry, Camille, Figueroa, Maria E., Vasanthakumar, Aparna, Patel, Jay, Zhao, Xinyang, Perna, Fabiana, Pandey, Suveg, Madzo, Jozef, Song, Chunxiao, Dai, Qing, He, Chuan, Ibrahim, Sherif, Beran, Miloslav, Zavadil, Jiri, Nimer, Stephen D., Melnick, Ari, Godley, Lucy A., Aifantis, Iannis, Levine, Ross L.
Publicado em 2011

Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer

Por Sansone, Pasquale, Ceccarelli, Claudio, Berishaj, Marjan, Chang, Qing, Rajasekhar, Vinagolu K., Perna, Fabiana, Bowman, Robert L., Vidone, Michele, Daly, Laura, Nnoli, Jennifer, Santini, Donatella, Taffurelli, Mario, Shih, Natalie N. C., Feldman, Michael, Mao, Jun J., Colameco , Christopher, Chen, Jinbo, DeMichele, Angela, Fabbri, Nicola, Healey, John H., Cricca, Monica, Gasparre, Giuseppe, Lyden, David, Bonafé, Massimiliano, Bromberg, Jacqueline
Publicado no Nat Commun (2016)

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

Por Moulick, Kamalika, Ahn, James H, Zong, Hongliang, Rodina, Anna, Cerchietti, Leandro, Gomes DaGama, Erica M, Caldas-Lopes, Eloisi, Beebe, Kristin, Perna, Fabiana, Hatzi, Katerina, Vu, Ly P, Zhao, Xinyang, Zatorska, Danuta, Taldone, Tony, Smith-Jones, Peter, Alpaugh, Mary, Gross, Steven S, Pillarsetty, Nagavarakishore, Ku, Thomas, Lewis, Jason S, Larson, Steven M, Levine, Ross, Erdjument-Bromage, Hediye, Guzman, Monica L, Nimer, Stephen D, Melnick, Ari, Neckers, Len, Chiosis, Gabriela
Publicado em 2011