Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon SDF-1 stimulation

Por Kumar, Ashok, Kremer, Kimberly N., Dominguez, Daniel, Tadi, Madhavi, Hedin, Karen E.
Publicado em 2010

Identification of unique MEK-dependent genes in GNAQ mutant uveal melanoma involved in cell growth, tumor cell invasion and MEK-resistance.

Por Ambrosini, Grazia, Pratilas, Christine A., Qin, Li-Xuan, Tadi, Madhavi, Surriga, Oliver, Carvajal, Richard D., Schwartz, Gary K.
Publicado em 2012

Arginine methyltransferase PRMT5 is essential for sustaining normal adult hematopoiesis

Por Liu, Fan, Cheng, Guoyan, Hamard, Pierre-Jacques, Greenblatt, Sarah, Wang, Lan, Man, Na, Perna, Fabiana, Xu, Haiming, Tadi, Madhavi, Luciani, Luisa, Nimer, Stephen D.
Publicado no J Clin Invest (2015)

The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner

Por Joseph, Eric W., Pratilas, Christine A., Poulikakos, Poulikos I., Tadi, Madhavi, Wang, Weiqing, Taylor, Barry S., Halilovic, Ensar, Persaud, Yogindra, Xing, Feng, Viale, Agnes, Tsai, James, Chapman, Paul B., Bollag, Gideon, Solit, David B., Rosen, Neal
Publicado em 2010

RELIEF OF PROFOUND FEEDBACK INHIBITION OF MITOGENIC SIGNALING BY RAF INHIBITORS ATTENUATES THEIR ACTIVITY IN BRAFV600E MELANOMAS

Por Lito, Piro, Pratilas, Christine A., Joseph, Eric W., Tadi, Madhavi, Halilovic, Ensar, Zubrowski, Matthew, Huang, Alan, Wong, Wai Lin, Callahan, Margaret K., Merghoub, Taha, Wolchok, Jedd D., de Stanchina, Elisa, Chandarlapaty, Sarat, Poulikakos, Poulikos I., Fagin, James A., Rosen, Neal
Publicado em 2012

Reactivation of ERK Signaling causes resistance to EGFR kinase inhibitors

Por Ercan, Dalia, Xu, Chunxiao, Yanagita, Masahiko, Monast, Calixte S., Pratilas, Christine A., Montero, Joan, Butaney, Mohit, Shimamura, Takeshi, Sholl, Lynette, Ivanova, Elena V., Tadi, Madhavi, Rogers, Andrew, Repellin, Claire, Capelletti, Marzia, Maertens, Ophélia, Goetz, Eva M., Letai, Anthony, Garraway, Levi A., Lazzara, Matthew J., Rosen, Neal, Gray, Nathanael S., Wong, Kwok-Kin, Jänne, Pasi A.
Publicado em 2012

RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

Por Poulikakos, Poulikos I., Persaud, Yogindra, Janakiraman, Manickam, Kong, Xiangju, Ng, Charles, Moriceau, Gatien, Shi, Hubing, Atefi, Mohammad, Titz, Bjoern, Gabay, May Tal, Salton, Maayan, Dahlman, Kimberly B., Tadi, Madhavi, Wargo, Jennifer A., Flaherty, Keith T., Kelley, Mark C., Misteli, Tom, Chapman, Paul B., Sosman, Jeffrey A., Graeber, Thomas G., Ribas, Antoni, Lo, Roger S., Rosen, Neal, Solit, David B.
Publicado em 2011