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Gα13 and Rho mediate endosomal trafficking of CXCR4 into Rab11+ vesicles upon SDF-1 stimulation

CXCR4, like other G protein coupled receptors (GPCRs), signals via heterotrimeric guanine nucleotide binding proteins (G proteins) to regulate gene transcription, migration, development, growth and transformation. We describe here a formerly-uncharacterized function of a G protein: a role in recepto...

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Detalles Bibliográficos
Main Authors: Kumar, Ashok, Kremer, Kimberly N., Dominguez, Daniel, Tadi, Madhavi, Hedin, Karen E.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057048/
https://ncbi.nlm.nih.gov/pubmed/21148034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002019
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